“41 | METABOLIC DYSREGULATION AND IMMUNE ACTIVATION IN VITILIGO: UNVEILING THE MITOCHONDRIAL AND INFLAMMATORY IMPRINT OF DISEASE PATHOGENESIS: S. Caputo1, A. Marini1, S. Scano1, F. Papaccio1, R. Marrapodi1, P. Iacovelli2, A. Presaghi3, E. Migliano3, C. Cota4, A. Filoni5, M. Picardo6, B. Bellei1 | 1Laboratory of Cutaneous Physiopathology and Integrated Center of Metabolomics Research, San Gallicano Dermatological Institute, IRCCS, Rome, Italy; 2Clinical Dermatology, Phototherapy Unit, San Gallicano Dermatological Institute, IRCCS, Rome, Italy; 3Department of Plastic and Regenerative Surgery, San Gallicano Dermatological Institute, IRCCS, Rome, Italy; 4Genetic Research, Molecular Biology and Dermatopathology Unit, San Gallicano Dermatological Institute, Rome, Italy; 5UOSVD Dermatology and Allergology, Hospital Vito Fazzi, Lecce, Italy; 6Istituto Dermopatico dell’Immacolata, IDI-IRCCS, Rome, Italy” (2026) Dermatology Reports, 18(s1). doi:10.4081/dr.2026.11065.