Abstracts
Vol. 2 No. 3 (2006)
https://doi.org/10.4081/hmr.v2i3.356

Alkylamines and bisphosphonates: a common mechanism for activation of

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Published: 5 June 2009
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K Thompson
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MJ Rogers
The major subset of gd T-cells in humans (Vg9Vd2+) are activated by three distinct classes of stimulatory molecules: pyrophosphomonoesters, such as isopentenyl diphosphate (IPP) and bromohydrin diphosphate (BrHPP); nitrogen-containing bisphosphonates (N-BPs), such as alendronate (ALN), pamidronate (PAM) and zoledronic acid (ZOL); and alkylamines, such as sec-butylamine (SBA) and iso-butylamine (IBA).

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Alkylamines and bisphosphonates: a common mechanism for activation of. (2009). Hematology Meeting Reports, 2(3). https://doi.org/10.4081/hmr.v2i3.356