Innovative treatments: bortezomib

PL Zinzani

doi:10.4081/hmr.v3i1.545

Abstracts

Vol. 3 No. 1 (2009)

https://doi.org/10.4081/hmr.v3i1.545

Innovative treatments: bortezomib

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Published: 11 June 2009

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PL Zinzani

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The incidence of non-Hodgkin's lymphoma (NHL) has markedly increased in the US and Western Europe in recent years and presents a considerable clinical challenge. Despite many advances in the treatment of NHL, the challenge to develop treatments far the disease remains. For example, there are few effective treatment options for patients with mantle celI lymphoma (MCL) and, while there are a number of therapies that can induce remission in patients with follicular lymphoma (FL), the disease remains incurable. Recently, preclinical and clinical studies have shown the potential for proteasome inhibition in the treatment of NHL.