Articoli originali
V. 13 (2025)
Gastrite: identificare i determinanti per la prevenzione delle complicanze. Un'analisi condotta su casi provenienti da un laboratorio italiano di patologia chirurgica
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Pubblicato: 22 dicembre 2025
794
Visite
170
Downloads
Autori
Background: a causa dell'impatto della gastrite sulla qualità della vita dei pazienti e dell'impor-tanza di una diagnosi accurata per identificare potenziali lesioni precancerose ad essa correlate, abbiamo valutato i determinanti che potrebbero influenzare maggiormente il rischio di sviluppo della gastrite e le alterazioni della mucosa gastrica. Materiali e Metodi: sono state raccolte biopsie gastriche eseguite da settembre a novembre 2023. Sono stati utilizzati modelli di regressione logistica univariata e multivariata per identifica-re i determinanti di gastrite, alterazioni della mucosa gastrica e gastrectomia (sleeve). I risultati del modello logistico sono stati presentati come Odds Ratio (OR) con un Intervallo di Confi-denza (IC) al 95% e il corrispondente p-value. Risultati: l'analisi logistica univariata e multivariata ha mostrato un aumento delle probabilità di sviluppo della gastrite in relazione all'età, mentre l'aumento delle probabilità di alterazioni gastri-che era legato anche al sesso. Il sesso maschile e l'età ≥65 anni hanno diminuito le probabilità di ricevere una resezione gastrica (sleeve). Conclusioni: è imperativo riconoscere i determinanti che hanno un maggiore impatto sullo svi-luppo della gastrite e delle alterazioni gastriche, al fine di identificare le persone più a rischio, in modo da poter valutare gli interventi preventivi a livello di popolazione.
Downloads
La data di download non è ancora disponibile.
Citations
1. Sipponen P, Maaroos HI. Chronic gastritis. Scand J Gastroenterol 2015;50:657-67. DOI: https://doi.org/10.3109/00365521.2015.1019918
2. Azer SA, Awosika AO, Akhondi H. Gastritis. 2024. Available from: https://www.ncbi.nlm.nih.gov/books/NBK544250/
3. Feyisa ZT, Woldeamanuel BT. Prevalence and associated risk factors of gastritis among patients visiting Saint Paul Hospital Millennium Medical College, Addis Ababa, Ethiopia. PLoS One 2021;16:e0246619. DOI: https://doi.org/10.1371/journal.pone.0246619
4. Pedroso Toscano E, Fernandez Madeira F, Pinheiro Dutra-Rulli M, et al. Epidemiological and clinical-pathological aspects of helicobacter pylori infection in Brazilian children and adults. Gastroenterology Research & Practice. 2018;2018:8454125. DOI: https://doi.org/10.1155/2018/8454125
5. Marcis L, Olga S, Jelizaveta P, Yaron N. Epidemiology of Helicobacter pylori infection. Wiley Helicobacter 2018;23:e12514. DOI: https://doi.org/10.1111/hel.12514
6. Geeraerts B, Vandenberghe J, Van Oudenhove L, et al. Influence of experimentally induced anxiety on gastric sensorimotor function in humans. Gastroenterology 2005;129:1437-44. DOI: https://doi.org/10.1053/j.gastro.2005.08.020
7. Cavatorta O, Scida S, Miraglia C, et al. Epidemiology of gastric cancer and risk factors. Acta Biomed 2018;89:82-7.
8. Laine L. Nonsteroidal anti-inflammatory drug gastropathy. Gastrointestinal endoscopy clinics of North America 1996;6:489-504. DOI: https://doi.org/10.1016/S1052-5157(18)30351-9
9. Farthing MJ, Fairclough PD, Hegarty JE, et al. Treatment of chronic erosive gastritis with prednisolone. Gut 1981;22:759-62. DOI: https://doi.org/10.1136/gut.22.9.759
10. Chen G, Yu Z, Zhang Y, et al. Radiation-induced gastric injury during radiotherapy: molecular mechanisms and clinical treatment. Journal of Radiation Research 2023;64:870-9. DOI: https://doi.org/10.1093/jrr/rrad071
11. Goel N, Levine MD, Chambers LM, Nagel CI. Gastritis as an immunotherapy-related toxicity in the treatment of endometrial cancer: A case report. Gynecol Oncol Rep 2023;47:101174. DOI: https://doi.org/10.1016/j.gore.2023.101174
12. Chen J, Ruan X, Fu T, et al. Sedentary lifestyle, physical activity, and gastrointestinal diseases: evidence from mendelian randomization analysis. EBioMedicine 2024;103:105110. DOI: https://doi.org/10.1016/j.ebiom.2024.105110
13. Zhang LY, Zhang J, Li D, et al. Bile reflux is an independent risk factor for precancerous gastric lesions and gastric cancer: an observational cross-sectional study. J Dig Dis 2021;22:282-90. DOI: https://doi.org/10.1111/1751-2980.12986
14. Lee JY, Park HW, Choi JY, et al. Helicobacter pylori Infection with Atrophic Gastritis Is an Independent Risk Factor for Advanced Colonic Neoplasm. Gut Liver 2016;10:902-9. DOI: https://doi.org/10.5009/gnl15340
15. Kim MK, Ko BJ, Kim EY, et al. Fast eating speed increases the risk of endoscopic erosive gastritis in Korean adults. Korean J Fam Med 2015;36:300-4. DOI: https://doi.org/10.4082/kjfm.2015.36.6.300
16. Singh S, Chakole S, Agrawal S, et al. A comprehensive review of upper gastrointestinal symptom management in autoimmune gastritis: current insights and future directions. Cureus 2023;15:e43418. DOI: https://doi.org/10.7759/cureus.43418
17. Misiewicz JJ. The Sydney System: a new classification of gastritis. Introduction. J Gastroenterol Hepatol 1991;6:207-8. DOI: https://doi.org/10.1111/j.1440-1746.1991.tb01467.x
18. Rugge M, Correa P, Di Mario F, et al. OLGA staging for gastritis: a tutorial. Dig Liver Dis 2008;40:650-8. DOI: https://doi.org/10.1016/j.dld.2008.02.030
19. Nikolova D, Trajkovska M, Trpcevska EN, et al. Evaluation of the effects of gastro protect as an alternative medicine on gastritis and other gastrointestinal symptoms. Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2024;45:51-60. DOI: https://doi.org/10.2478/prilozi-2024-0006
20. Mogami S, Arita R, Nahata M, et al. Usefulness of a Kampo medicine on stress-induced delayed gastric emptying in mice. Evid Based Complement Alternat Med 2020;2020:3797219. DOI: https://doi.org/10.1155/2020/3797219
21. Sun Y, Yin L, Nesheli DN, et al. Overall and cause-specific mortality among patients diagnosed with gastric precancerous lesions in Sweden between 1979 and 2014: an observational cohort study. BMC Med 2024;22:333. DOI: https://doi.org/10.1186/s12916-024-03554-1
22. Park JB, Koo JS. Helicobacter pylori infection in gastric mucosa-associated lymphoid tissue lymphoma. World J Gastroenterol 2014;20:2751-9. DOI: https://doi.org/10.3748/wjg.v20.i11.2751
23. Jencks DS, Adam JD, Borum ML, et al. Overview of current concepts in gastric intestinal metaplasia and gastric cancer. Gastroenterol Hepatol (NY) 2018;14:92-101.
24. Chivu R, Evanghelides A, Georgescu DE, Pa Traşcu T. Navigating through surgical implications of Helicobacter pylori: an up-to-date comprehensive literature review. Chirurgia (Bucur). 2023;118:568-83. DOI: https://doi.org/10.21614/chirurgia.2023.v.118.i.6.p.568
25. Emerenziani S, Guarino MPL, Trillo Asensio LM, et al. Role of overweight and obesity in gastrointestinal disease. Nutrients 2019;12:111. DOI: https://doi.org/10.3390/nu12010111
26. Turnip ED, Indriarini MY, Wijaya YM. Unhealthy lifestyle among sufferers of gastritis on young adult age. Jurnal Berita Ilmu Keperawatan 2023;16:232-9. DOI: https://doi.org/10.23917/bik.v16i2.2346
Come citare
Gastrite: identificare i determinanti per la prevenzione delle complicanze. Un’analisi condotta su casi provenienti da un laboratorio italiano di patologia chirurgica. (2025). Working Paper of Public Health, 13. https://doi.org/10.4081/wpph.2025.10180
Copyright (c) 2025 Sara Biasion, Stefania Erra, Carlotta Bertolina, Riccardo Mazzucco, Giovanni Angeli, Elia Ranzato, Marinella Bertolotti, Antonio Maconi
Questo volume è pubblicato con la licenza Creative Commons Attribuzione - Non commerciale 4.0 Internazionale.
