Case Reports

Mycoplasma pneumoniae-induced rash and mucositis: two case reports and literature review

Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Published: 31 March 2026
68
Views
42
Downloads

Authors

Mycoplasma pneumoniae is one of the most prevalent pathogens involved in respiratory infections. A new syndrome characterized by prominent mucositis and sparse cutaneous involvement related to the infection has recently been described. We report two clinical cases from our Dermatological Department.

Downloads

Download data is not yet available.

Citations

1. Kumar S. Mycoplasma pneumoniae: A significant but underrated pathogen in paediatric com-munity-acquired lower respiratory tract infections. Indian J Med Res 2018;147:23.
2. Hammerschlag MR. Mycoplasma pneumoniae infections. Curr Opinion Infect Dis 2001;14:181-6.
3. Poddighe D. Extra-pulmonary diseases related to Mycoplasma pneumoniae in children: recent insights into the pathogenesis. Curr Opin Rheumatol 2018;30:380-7.
4. Frantz, GF, McAninch SA. Mycoplasma pneumoniae-Induced Rash and Mucositis (MIRM). In StatPearls. StatPearls Publishing, 2024.
5. Vujic I, Shroff A, Grzelka M, et al. Mycoplasma pneumoniae-associated mucositis--case report and systematic review of literature. J Eur Acad Dermatol Venereol 2015;29:595-8.
6. Canavan TN, Mathes EF, Frieden I, Shinkai K. Mycoplasma pneumoniae-induced rash and mucositis as a syndrome distinct from Stevens-Johnson syndrome and erythema multiforme: a systematic review. J Am Acad Dermatol 2015;72:239-45.
7. Al-Zaidy SA, MacGregor D, Mahant S, et al. Neurological complications of PCR-Proven M. pneumoniae infections in children: prodromal illness duration may reflect pathogenetic mechanism. Clin Infect Dis 2015;61:1092-8.
8. Ashtekar CS, Jaspan T, Thomas D, et al. Acute bilateral thalamic necrosis in a child with Mycoplasma pneumoniae. Dev Med Child Neurol 2003;45:634-7.
9. Santos RP, Silva M, Vieira AP, Brito C. Mycoplasma pneumoniae-induced rash and mucositis: a recently described entity. BMJ Case Rep 2017;2017:bcr-2017
10. Kucharek I, Bednarz K, Sybilski AJ. Unique presentation of Mycoplasma pneumoniae-Induced Rash and Mucositis with Salivary Gland Inflammation in a Pediatric Patient: A Case Report. J Clin Med 2024;13:4587.
11. Brazel D, Kulp B, Bautista G, Bonwit A. Rash and mucositis associated with Mycoplasma pneumoniae and Chlamydophila pneumoniae: A Recurrence of MIRM? J Pediatric Infect Dis Soc 2021;10:220-4.
12. Zão I, Ribeiro F, Rocha V, et al. Mycoplasma pneumoniae-associated mucositis: A Recently Described Entity. Eur J Case Rep Intern Med 2018;5:000977.
13. Bowling M, Schmutzler T, Glick S. Mycoplasma pneumoniae-induced mucositis without rash in an 11-year-old boy. Clin Case Rep 2018;6:551-2.
14. Curtiss P, Melnick L, Sicco KL, Liebman TN. Mycoplasma pneumoniae, more than a lung disease. Dermatol Online J 2018;24:13030/qt8w993185.
15. Song H, Huang JT, Tan JK. Mycoplasma-Induced Rash and Mucositis in a father and son: A Case Report. Pediatr Infect Dis J 2018;37:e205-6.
16. Sandhu R, Mareddy C, Itskowitz M, et al. Mycoplasma-induced rash and mucositis in a young patient with red eyes, oral mucositis, and targetoid cutaneous vesicles. Lancet Infect Dis 2017;17:562.

How to Cite



1.
Sabbadini C, Mariotti I, Tei L, Cassar W, Nobile C. Mycoplasma pneumoniae-induced rash and mucositis: two case reports and literature review. Dermatol Reports [Internet]. 2026 Mar. 31 [cited 2026 Apr. 19];. Available from: https://journals.pagepress.net/dr/article/view/10336