Letters to the Editor
Early Access
https://doi.org/10.4081/dr.2026.10537

Hand, foot, and mouth disease progressing into sialadenitis in an adult patient: a rare complication

Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Published: 16 January 2026
305
Views
181
Downloads
Adult, Coxsackievirus, hand, foot, and mouth disease, oral ulcers, sialadenitis

Authors

Raghad Abdeljawad
Jordanian Royal Medical Services, Amman, Jordan.
Osama Abu-Hammad
School of Dentistry, University of Jordan, Amman, Jordan.
Omayyah Dar-Odeh
Private Practice, Amman, Jordan.
Rua'a Abdeljawad
Private Practice, Amman, Jordan.
Douleh Alfataftah
Faculty of Dentistry, An-Najah National University, Nablus, Palestine, State of.
Rahaf Abdeljawad
School of Medicine, Hashemite University, Zarqa, Jordan.
Najla Dar-Odeh
najla@ju.edu.jo
School of Dentistry, University of Jordan, Amman, Jordan.

Dear Editor,

In April 2024, a 24-year-old non-smoker female patient with controlled asthma presented with a sore throat, left-sided cervical lymphadenopathy, and a painful, red maculopapular rash on the hands and feet. [...]

Downloads

Download data is not yet available.

Citations

Crossref
Scopus
Google Scholar
Europe PMC
1. Kimmis BD, Downing C, Tyring S. Hand-foot-and-mouth disease caused by coxsackievirus A6 on the rise. Cutis 2018;102:353-6.
2. Sun BJ, Chen HJ, Chen Y, et al. The risk factors of acquiring severe hand, foot, and mouth disease: A meta-analysis. Can J Infect Dis Med Microbiol 2018. DOI: https://doi.org/10.1155/2018/2751457
3. Lim B-K, Ju E-S, Lao DH, et al. Development of a enterovirus diagnostic assay system for diagnosis of viral myocarditis in humans. Microbiol Immunol 2013;57:281-7. DOI: https://doi.org/10.1111/1348-0421.12028
4. Muehlenbachs A, Bhatnagar J, Zaki SR. Tissue tropism, pathology and pathogenesis of enterovirus infection. Journal Pathol 2015;235:217-28. DOI: https://doi.org/10.1002/path.4438
5. Ciccarese G, Broccolo F, Fidanzi C, et al. Atypical hand foot and mouth disease related Coxsackievirus-A10 infection in an adult patient. Travel Med Infect Dis 2024;59:102716. DOI: https://doi.org/10.1016/j.tmaid.2024.102716
6. Yüksel S, Evrengül H, Özhan B, et al. Onychomadesis—A Late Complication of Hand-Foot-Mouth Disease. J Pediatr 2016;174:274. DOI: https://doi.org/10.1016/j.jpeds.2016.03.073
7. Zhou H-T, Wang B, Che X-Y. Nephrotic syndrome in hand, foot and mouth disease caused by coxsackievirus A16: a case report. Int J Infect Dis 2014;28:1-2. DOI: https://doi.org/10.1016/j.ijid.2014.04.031
8. Batts AF, Jalalat SZ, Hunter-Ellul L, et al. Exacerbation of bullous pemphigoid after hand, foot, and mouth disease treated with rituximab. JAAD Case Re 2016;2:7-9. DOI: https://doi.org/10.1016/j.jdcr.2015.11.006
9. Yamamoto Y, Matsumura M. Adult Hand, Foot, and Mouth Disease. Am J Med 2023;136:e231-2. DOI: https://doi.org/10.1016/j.amjmed.2023.08.006
10. Loustalot F, Kremer EJ, Salinas S. Chapter Six - Membrane Dynamics and Signaling of the Coxsackievirus and Adenovirus Receptor. In: Jeon KW (ed) International Review of Cell and Molecular Biology. Academic Press, pp. 331-362.

How to Cite



1.
Abdeljawad R, Abu-Hammad O, Dar-Odeh O, Abdeljawad R, Alfataftah D, Abdeljawad R, et al. Hand, foot, and mouth disease progressing into sialadenitis in an adult patient: a rare complication. Dermatol Reports [Internet]. 2026 Jan. 16 [cited 2026 May 25];. Available from: https://journals.pagepress.net/dr/article/view/10537
Copyright (c) 2026 the Author(s) Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.