Case Reports

Solitary hemorrhagic cutaneous mastocytoma of infancy with digital localization: a case report

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Published: 8 July 2026
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Solitary cutaneous mastocytoma is the most common form of pediatric cutaneous mastocytosis and usually follows a benign, self-limited course. However, atypical clinical presentations such as hemorrhagic or bullous evolution and uncommon anatomical localization may raise diagnostic concerns and lead to unnecessary investigations. We report the case of a male infant presenting with a solitary hemorrhagic mastocytoma localized on a finger. The lesion showed episodic blistering and hemorrhage after minimal mechanical stimulation, without systemic symptoms. Dermoscopic examination revealed a structureless erythematous-violaceous background without melanocytic features. Histopathological analysis demonstrated a dense dermal mast cell infiltrate with strong CD117 and CD25 expression, confirming the diagnosis. Conservative management resulted in spontaneous regression without sequelae. This case highlights the importance of clinicopathological correlation in recognizing atypical presentations of solitary mastocytoma and avoiding misdiagnosis and overtreatment.

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Citations

1. Sathishkumar D, Balasundaram A, Mathew SM, et al. Clinicopathological Profile of Childhood Onset Cutaneous Mastocytosis from a Tertiary Care Center in South India. Indian Dermatol Online J 2021;12:706-13.
2. Leung AKC, Lam JM, Leong KF. Childhood Solitary Cutaneous Mastocytoma: Clinical Manifestations, Diagnosis, Evaluation, and Management. Curr Pediatr Rev 2019;15:42-6.
3. Kacker A, Huo J, Huang R, Hoda RS. Solitary mastocytoma in an infant - case report with review of literature. Int J Pediatr Otorhinolaryngol 2000;52:93-5.
4. Neri I, Rapparini L, Salamone FP, et al. Hemorrhagic Blister in an Infant. Dermatol Pract Concept 2023;13:e2023200.

How to Cite



1.
Barbato F, Damiani L, Gaudiello F, Iandolo M, Calandriello G, Licata G, et al. Solitary hemorrhagic cutaneous mastocytoma of infancy with digital localization: a case report. Dermatol Reports [Internet]. 2026 Jul. 8 [cited 2026 Sep. 4];. Available from: https://journals.pagepress.net/dr/article/view/10834