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The humanistic burden of atopic dermatitis in Greece: a cross-sectional study

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Received: 9 October 2024
Accepted: 4 March 2025
Published: 9 April 2025
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The purpose of this study was to evaluate the quality of life (QoL) and psychosocial burden in adult Greek patients with atopic dermatitis (AD) using validated tools and to investigate factors that influence AD’s humanistic burden. This observational, cross-sectional study was conducted in Greece (January-September 2023) with 150 adult members of the patient association “Epidermia”, all diagnosed with AD. Data was collected through a structured questionnaire, including socio-demographic details, clinical history, AD severity (using the Patient-Oriented Eczema Measure [POEM]), QoL, sleep disorders, and psychological health. Based on POEM scores, 11% of participants had clear/almost clear skin, 27% had mild eczema, 51% had moderate eczema, and 12% had severe/very severe eczema. AD had a moderate or very/extremely large impact on QoL for 29% and 42% of participants, respectively. Insomnia affected 55%, while 31% had mild anxiety, 23% had moderate/severe anxiety, 10% had moderate depression, and 8% had moderately severe/severe depression. AD severity was associated with reduced QoL and higher rates of insomnia, anxiety, and depression. Our study highlights significant associations between AD severity, QoL, and psychosocial factors, emphasizing the need for comprehensive management strategies.

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Supporting Agencies

The project described in this article was supported by a grant from Pfizer Global Medical Grants. The grant was awarded through a proposal/protocol selection process in a competition titled “Quantifying the Socio-Economic Burden of Disease for Dermatology Patients and Caregivers Competitive Grant Program”. The funding sponsor of this study did not participate in the design and conduct of the study, collection, management, analysis, and interpretation of the data, or preparation, review, or approval of the manuscript. Its contents are solely the responsibility of the authors.

How to Cite



1.
Kourlaba G, Lioliou K, Stefanou G, Koukopoulou S, Vamvakousis E, Ioannides D. The humanistic burden of atopic dermatitis in Greece: a cross-sectional study. Dermatol Reports [Internet]. 2025 Apr. 9 [cited 2026 May 4];17(4). Available from: https://journals.pagepress.net/dr/article/view/10164