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Successful treatment of refractory generalized granuloma annulare with abrocitinib

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Published: 23 January 2026
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Dear Editor,

Granuloma annulare is a chronic inflammatory skin disorder characterized by annular dermal papules and plaques. While localized forms often resolve spontaneously, generalized granuloma annulare tends to persist and frequently proves resistant to conventional therapies. The pathogenesis of the disease remains unclear, but increasing evidence suggests a dysregulated immune response involving T cells, macrophages, and cytokines such as tumor necrosis factor-alpha (TNF-α), interleukin (IL)-6, and interferon-gamma (IFN-γ). [...]

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Citations

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How to Cite



1.
Giorgio CM, Balato A, Licata G, Tancredi V, Argenziano G, Di Brizzi EV. Successful treatment of refractory generalized granuloma annulare with abrocitinib. Dermatol Reports [Internet]. 2026 Jan. 23 [cited 2026 May 24];. Available from: https://journals.pagepress.net/dr/article/view/10296