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A rare presentation of infantile hemangioma with minimal or arrested growth in PHACE(S) syndrome
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Published: 23 January 2026
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Authors
Dear Editor,
PHACE(S) syndrome is a neurocutaneous disorder associated with segmental infantile hemangiomas (IHs). These hemangiomas typically manifest as rapidly growing lesions on the face or upper trunk. However, this case presents an unusual phenotype – an IH with minimal or arrested growth (IHMAG). [...]
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Citations
1. Metry D, Heyer G, Hess C, et al. Consensus statement on diagnostic criteria for PHACE syndrome. Pediatrics 2009;124:1447-56. DOI: https://doi.org/10.1542/peds.2009-0082
2. Cohen BA, Frieden IJ, Püttgen KB, et al. Infantile hemangiomas with minimal or arrested growth: a retrospective case series. Pediatr Dermatol 2017;34:64-70.
3. Finstad A, Lytvyn Y, Pope E, Sibbald C. Safety of beta blockers for the treatment of PHACE syndrome: a systematic review. J Am Acad Dermatol 2025:S0190-9622(25)00048-9.
4. Siegel DH, Tefft KA, Kelly T, et al. Stroke in children with posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, and eye abnormalities (PHACE) syndrome: a systematic review of the literature. Stroke 2012;43:1672-4. DOI: https://doi.org/10.1161/STROKEAHA.112.650952
How to Cite
1.
Barbato F, Licata G, Benvenuto P, Esposito F, Petrone E, Giorgio CM. A rare presentation of infantile hemangioma with minimal or arrested growth in PHACE(S) syndrome. Dermatol Reports [Internet]. 2026 Jan. 23 [cited 2026 May 19];. Available from: https://journals.pagepress.net/dr/article/view/10351
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