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Dermoscopic features of amelanotic cutaneous melanoma metastases: evidence from four cases
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Published: 7 April 2026
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Cutaneous metastases of malignant melanoma (MM) are relatively common, occurring in 2-20% of cases. These metastases typically present as pigmented papules or nodules but can occasionally manifest in unusual forms, such as amelanotic cutaneous melanoma metastases (ACMMs). Due to their relative rarity (less than one-third of cutaneous metastases of MM), definitive dermoscopic characterization of ACMMs remains elusive. This case series investigates the dermoscopic features of four ACMM cases, all of which exhibited vascular patterns. Consolidating our findings with existing literature, polymorphic vessels and linear irregular/serpentine vessels emerge as the predominant patterns in ACMMs. Notably, in one case, the primary melanoma was initially unrecognized, with metastases appearing as the initial manifestation of the disease. This series underscores the need to establish precise dermoscopic criteria for ACMMs.
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How to Cite
1.
Campoli M, Barlusconi C, Zerbinati N, Lombardo M. Dermoscopic features of amelanotic cutaneous melanoma metastases: evidence from four cases. Dermatol Reports [Internet]. 2026 Apr. 7 [cited 2026 Apr. 18];. Available from: https://journals.pagepress.net/dr/article/view/10425
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