Letters to the Editor
Early Access
Membranous aplasia cutis congenita
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Published: 17 November 2025
143
Views
59
Downloads
Authors
Dear Editor,
Aplasia cutis congenita (ACC) is a rare congenital malformation characterized by the focal absence of skin visible at birth, most frequently involving the scalp, although any part of the body may be affected. The estimated incidence is approximately 1 to 3 per 10,000 live births. The pathogenesis is heterogeneous and yet not fully understood. [...]
Downloads
Download data is not yet available.
Citations
1. Higgins C, Price A, Craig S. Aplasia cutis congenita. BMJ Case Rep 2022;15:e251533. DOI: https://doi.org/10.1136/bcr-2022-251533
2. Schierz IAM, Giuffrè M, Del Vecchio A, et al. Recognizable neonatal clinical features of aplasia cutis congenita. Ital J Pediatr 2020;46:25. DOI: https://doi.org/10.1186/s13052-020-0789-5
3. Colon-Fontanez F, Fallon Friedlander S, Newbury R, Eichenfield LF. Bullous aplasia cutis congenita. J Am Acad Dermatol 2003;48:S95-8. DOI: https://doi.org/10.1067/mjd.2003.150
4. She QY, Zhu HL, Liu ZR, Huang WN. Membranous aplasia cutis congenita: A rare case report highlighting clinical presentation, genetic insights, and the need for comprehensive evaluation. Heliyon 2024;10:e33742. DOI: https://doi.org/10.1016/j.heliyon.2024.e33742
5. Zhang L, Zhang Z, Jiang HJ, et al. Dermoscopic characteristics of membranous aplasia cutis congenita: Report of 56 cases. Skin Res Technol 2022;28:792-5. DOI: https://doi.org/10.1111/srt.13200
6. Lozano-Masdemont B. A Case of Membranous Aplasia Cutis Congenita and Dermoscopic Features. Int J Trichology 2017;9:33-4. DOI: https://doi.org/10.4103/ijt.ijt_91_16
7. Kwon HS, Lee JH, Bae JM, Kim GM. Case of linear bullous aplasia cutis congenita. J Dermatol 2017;44:e310-1. DOI: https://doi.org/10.1111/1346-8138.13972
8. Cammarata-Scalisi F, Diociaiuti A, de Guerrero B, et al. Membranous aplasia cutis congenita in trisomy 18. Ital J Pediatr 2020;46:120. DOI: https://doi.org/10.1186/s13052-020-00885-6
9. AlMatrafi FR, Al-Shammari AA, Al Nefily RM, et al. Case report: Aplasia cutis congenita of the scalp with bone defect and an exposed sagittal sinus in a trisomy 13 newborn. Front Pediatr 2023;11:1142950. DOI: https://doi.org/10.3389/fped.2023.1142950
10. Drolet B, Prendiville J, Golden J, et al. ‘Membranous aplasia cutis’ with hair collars. Congenital absence of skin or neuroectodermal defect? Arch Dermatol 1995;131:1427-31. DOI: https://doi.org/10.1001/archderm.1995.01690240091015
How to Cite
1.
Poddine G, Salvagno S, Bellinato F, Gisondi P, Girolomoni G. Membranous aplasia cutis congenita. Dermatol Reports [Internet]. 2025 Nov. 17 [cited 2026 Apr. 24];. Available from: https://journals.pagepress.net/dr/article/view/10544
Copyright (c) 2025 the Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
