Letters to the Editor

A young case of digital papillary adenocarcinoma successfully treated by wide local excision

Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Published: 3 April 2026
86
Views
21
Downloads

Authors

Dear Editor,

Digital papillary adenocarcinoma (DPA) is a rare malignant tumor originating from the sweat glands, predominantly affecting the digits of middle-aged to elderly individuals, with a higher incidence in males. DPA presents as a painless, slow-growing nodule on the fingers or toes, often leading to delayed diagnosis. DPA is characterized by complex papillary and tubular structures, cytologic atypia, and frequent mitotic figures. Due to its propensity for local recurrence and distant metastasis, early detection and local excision with clear margins are crucial for effective management. Regular long-term follow-up is recommended to monitor for recurrence or metastasis. Here, we present a young case of DPA located on the hand successfully treated by wide local excision. [...]

Downloads

Download data is not yet available.

Citations

1. Suchak R, Wang WL, Prieto VG, et al. Cutaneous digital papillary adenocarcinoma: a clinicopathologic study of 31 cases of a rare neoplasm with new observations. Am J Surg Pathol 2012;36:1883-91.
2. Bryant JR, Gardner P, Yousif M, et al. Aggressive Digital Papillary Adenocarcinoma of the Hand Presenting as a Felon. Case Rep Orthop 2017;2017:6456342.
3. Jabbour AJ, Tangoren IA, Kanik AB. Digital Papillary Adenocarcinoma: Case of a Rare Malignant Cutaneous Tumor of the Eccrine Sweat Gland. Case Rep Dermatol 2021;13:422-7.
4. Vanderbilt C, Brenn T, Moy AP, et al. Association of HPV42 with digital papillary adenocarcinoma and the use of in situ hybridization for its distinction from acral hidradenoma and diagnosis at non-acral sites. Mod Pathol 2022;35:1405-10.
5. Molina-Ruiz AM, Llamas-Velasco M, Rütten A, et al. “Apocrine Hidrocystoma and Cystadenoma”-like Tumor of the Digits or Toes: A Potential Diagnostic Pitfall of Digital Papillary Adenocarcinoma. Am J Surg Pathol 2016;40:410-8.

How to Cite



1.
Hachiken H, Fukumoto T, Yagita T, Kinusada M, Kubo A. A young case of digital papillary adenocarcinoma successfully treated by wide local excision. Dermatol Reports [Internet]. 2026 Apr. 3 [cited 2026 Apr. 18];. Available from: https://journals.pagepress.net/dr/article/view/10646