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https://doi.org/10.4081/dr.2026.10817

The association between serum leptin level and the atherogenic index of plasma in psoriatic patients

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Published: 26 August 2026
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Leptin, atherogenic index, psoriasis

Authors

Samer A. Dhaher
samer.dhaher@uobasrah.edu.iq
Department of Dermatology, College of Medicine, University of Basrah, Iraq.
Budoor O. Yousif
Department of Dermatology, Basrah Teaching Hospital, Iraq.
Nazar S. Haddad
Department of Biochemistry, College of Medicine, University of Basrah, Iraq.

Psoriatic patients have increased cardiometabolic risk and elevated serum leptin levels; however, the association between these factors remains unknown. In this report, serum leptin and the atherogenic index of plasma (AIP) were measured in a cross-sectional study of 100 patients with psoriasis. The results showed that the mean ± standard deviation (SD) serum leptin was 19.9±9.7 ng/mL. AIP was 0.3±0.06; 46% of patients were classified as low risk, 15% as intermediate risk, and 39% as high risk. Leptin levels increased with age, body mass index (BMI), and AIP and were associated with a twofold increase in the likelihood of elevated AIP (odds ratio [OR]=2.0; p=0.025). AIP was an independent predictor for higher leptin levels. These data suggest that serum leptin and AIP are linked in psoriasis and may reflect a shared inflammatory mechanism that contributes to increased cardiovascular risk.

 

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How to Cite



1.
Dhaher SA, Yousif BO, Haddad NS. The association between serum leptin level and the atherogenic index of plasma in psoriatic patients. Dermatol Reports [Internet]. 2026 Aug. 26 [cited 2026 Sep. 9];. Available from: https://journals.pagepress.net/dr/article/view/10817
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