Letters to the Editor

Widespread dermoscopic alterations of multiple melanocytic nevi in a patient receiving vandetanib: implications for dermatological surveillance

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Published: 12 May 2026
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Dear Editor,

Regression-like dermoscopic and histopathological changes in pre-existing melanocytic nevi have increasingly been reported in patients undergoing modern oncologic therapies, particularly immune checkpoint inhibitors (such as ipilimumab, nivolumab, and pembrolizumab) and targeted agents including BRAF and MEK inhibitors. [...]

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Citations

1. Belkaid S, Clerc M, Amini-Adle M, et al. Association of dermoscopic signs of regression in melanocytic lesions with immune checkpoint inhibitor response in metastatic melanoma patients. J Eur Acad Dermatol Venereol 2025;39:e600-3.
2. Perier-Muzet M, Boespflug A, Poulalhon N, et al. Dermoscopic evaluation of melanocytic nevi changes with combined mitogen-activated protein kinase pathway inhibitors therapy for melanoma. JAMA Dermatol 2016;152:1162-4.
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9. Joshi SS, Ortiz S, Witherspoon JN, et al. Effects of epidermal growth factor receptor inhibitor-induced dermatologic toxicities on quality of life. Cancer 2010;116:3916-23.

How to Cite



1.
Paolino G, Di Nicola MR, Rizzo N, Mercuri SR. Widespread dermoscopic alterations of multiple melanocytic nevi in a patient receiving vandetanib: implications for dermatological surveillance. Dermatol Reports [Internet]. 2026 May 12 [cited 2026 Jun. 3];. Available from: https://journals.pagepress.net/dr/article/view/10851