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Concomitant oral and genital mucosal involvement in classical Sweet syndrome

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Published: 2 September 2026
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Dear Editor,

Sweet syndrome (SS) is a rare inflammatory dermatosis characterized by the abrupt onset of painful erythematous plaques, papules and nodules associated with a neutrophilic dermal infiltrate, fever, and peripheral neutrophilia. It is classified into three major subtypes: the classical form, frequently associated with infections, pregnancy, inflammatory bowel disease and other autoimmune disorders; the malignancy-associated form, linked to both solid-organ and hematologic malignancies, particularly acute myeloid leukemia and myelodysplastic syndromes; and the drug-induced form. [...]

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Citations

1. Griffiths CEM, Barker JNWN, Bleiker TO, et al., eds. Rook’s textbook of dermatology. 10th ed. Wiley-Blackwell; 2024.
2. Cohen PR. Sweet’s syndrome--a comprehensive review of an acute febrile neutrophilic dermatosis. Orphanet J Rare Dis 2007;2:34.
3. Orfaly VE, Shakshouk H, Heath M, et al. Sweet Syndrome: A Review of Published Cases. Dermatology 2023;239:664-9.
4. von den Driesch P, Steffan C, Zöbe A, Hornstein OP. Sweet’s syndrome--therapy with cyclosporin. Clin Exp Dermatol 1994;19:274-7.
5. Su WP, Liu HN. Diagnostic criteria for Sweet’s syndrome. Cutis 1986;37:167-74.
6. Raza S, Kirkland RS, Patel AA, et al. Insight into Sweet’s syndrome and associated-malignancy: a review of the current literature. Int J Oncol 2013;42:1516-22.

How to Cite



1.
Ragonesi S, Corio A, Di Salvatore A, di Meo N, Di Bella S, Zalaudek I. Concomitant oral and genital mucosal involvement in classical Sweet syndrome. Dermatol Reports [Internet]. 2026 Sep. 2 [cited 2026 Sep. 3];. Available from: https://journals.pagepress.net/dr/article/view/10915