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  12 | Integrated molecular and immunophenotypic profiling of uveal melanoma: prognostic insights and biological perspectives Francesco Fortarezza¹, Giovanni Zarrilli², Giada Munari¹, Valentina Angerilli³, Mariangela Balistreri¹, Luisa Piccin⁴, Valentina Salizzato⁴, Jacopo Pigozzo⁴, Giulia Midena⁵, Raffaele Parrozzani⁶, Valentina Guarneri^4|7, Edoardo Midena^5|6, Marta Sbaraglia^1|8, Matteo Fassan^8|9, Angelo Paolo Dei Tos^1|8 | ¹Surgical Pathology and Cytopathology Unit, Department of Integrated Diagnostics. Azienda Ospedale-Università Padova, Padua; ²Surgical Pathology Unit, Azienda Ulss 3 Serenissima, Ospedale dell'Angelo, Venezia; ³Department of Surgical Pathology, Azienda ULSS2 Marca Trevigiana, Treviso; ⁴Medical Oncology 2, Veneto Institute of Oncology, IOV-IRCCS, Padua; ⁵IRCCS-Fondazione Bietti, Rome; ⁶Department of Ophthalmology, University of Padova, Padova; ⁷Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua; ⁸Department of Medicine, University of Padua School of Medicine, Padua; ⁹Veneto Institute of Oncology, IOV-IRCCS, Padua, Italy.

  Italian Melanoma Intergroup

  11-12-2025

  https://doi.org/10.4081/dr.2025.10754

  310
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  05 | Revisiting cancer risk associated with the MITF p.e318k variant beyond melanoma Debora Tonello¹, Beatrice Zennaro¹, Stefania Pellegrini¹, Monica Quaggio², Luisa Piccin³, Alessio Fabozzi⁴, Luigi Dall’Olmo^2|5, Saveria Tropea⁵, Maria Chiara Scaini¹, Chiara Menin¹ | ¹Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, Padova; ²Department of Surgery, Oncology and Gastroenterology, Section of Immunology and Oncology, AIDS Reference Center, University of Padova, Padova; ³Medical Oncology 2, Veneto Institute of Oncology IOV-IRCCS, Padova; ⁴Oncology Unit 3, Veneto Institute of Oncology - IOV-IRCCS, Padua; ⁵Soft-Tissue, Peritoneum, and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.

  Italian Melanoma Intergroup

  11-12-2025

  https://doi.org/10.4081/dr.2025.10747

  342
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  32 | Tebentafusp in metastatic uveal melanoma: 3 years of real world data and insights from liquid biopsy Luisa Piccin¹, Maria Chiara Scaini², Valentina Salizzato¹, Cristina Catoni², Elisabetta Di Liso¹, Alice Menichetti¹, Chiara Cacco^1|4, Chiara Gottardi^1|4, Francesca Di Sarra³, Marina Coppola³, Valentina Guarneri^1|4, Jacopo Pigozzo¹ | ¹Medical Oncology 2 - Veneto Institute of Oncology IOV-IRCCS; ²Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV-IRCCS; ³Pharmacy Unit - Veneto Institute of Oncology IOV-IRCCS; ⁴Department of Surgery, Oncology and Gastroenterology, University of Padova, Italy.

  Italian Melanoma Intergroup

  11-12-2025

  https://doi.org/10.4081/dr.2025.10774

  270
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  31 | Effectiveness and safety of adjuvant combo-targeted and immunotherapy in melanoma patients Valentina Salizzato¹, Luisa Piccin¹, Alessio Fabozzi², Paolo Del Fiore³, Francesco Cavallin⁴, Chiara Cacco^1|5, Simone Mocellin^3|5, Marcodomenico Mazza³, Valentina Guarneri^1|5, Jacopo Pigozzo¹ | ¹Medical Oncology 2, Veneto Institute of Oncology IOV-IRCCS, Padova; ²Medical Oncology 3, Veneto Institute of Oncology IOV-IRCCS, Padova; ³Soft-Tissue, Peritoneum and Melanoma Surgical Oncology, Veneto Institute of Oncology IOV-IRCCS, Padova; ⁴Independent Statistician, Solagna; ⁵Department of Surgical, Oncological and Gastroenterological Sciences, University of Padova, Padova, Italy.

  Italian Melanoma Intergroup

  11-12-2025

  https://doi.org/10.4081/dr.2025.10773

  275
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  29 | The extracellular vesicle potential for the early detection of resistance to immunotherapy in melanoma patients Cristina Catoni¹, Cristina Poggiana¹, Alessandro Francesco Piazza¹, Jacopo Pigozzo², Luisa Piccin², Chiara Menin¹, Stefania Pellegrini¹, Valentina Salizzato², Paolo Del Fiore⁴, Simone Mocellin^3|4, Vanna Chiarion-Sileni², Valentina Guarneri^2|3, Antonio Rosato^1|3, Maria Chiara Scaini¹ | ¹Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, Padua; ²Medical Oncology 2, Veneto Institute of Oncology, IOV-IRCCS, Padua; ³Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua; ⁴Soft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.

  Italian Melanoma Intergroup

  11-12-2025

  https://doi.org/10.4081/dr.2025.10771

  277