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24 | Management of advanced basal cell carcinoma with hedgehog inhibitors: a real-world prospective comparative study Federico Venturi1|2|3, Biancamaria Zuccaro1, Gabriella Perillo1, Giovanni Cecchi1, Aurora Gaeta4|5, Sara Gandini4, Vincenzo De Giorgi1|6 | 1Section of Dermatology, Department of Health Sciences, University of Florence; 2Oncologic Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna; 3Department of Medical and Surgical Sciences, DIMEC, Alma Mater Studiorum University of Bologna; 4Department of Experimental Oncology, European Institute of Oncology, IRCCS, Milan; 5Department of Statistics and Quantitative Methods, University of Milano-Bicocca; 6Cancer Research "Attilia Pofferi" Foundation, Pistoia, Italy.
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25 | A phase II, open-label study to improve compliance and time of treatment after obtaining complete response through a tailored schedule of sonidegib in locally advanced basal cell carcinomas – the SONIBEC trial Monica Variolo1|2, Carlo Resteghini1|2, Sara Farinatti1|2, Andrea Alberti3, Valeria Tovazzi3, Paola Queirolo4, Maristella Saponara4, Giuseppe Argenziano5, Riccardo Marconcini6, Ketty Peris7, Paola Savoia8, Maria Chiara Tronconi1, Iris Zalaudek9, Paolo Ascierto10, Francesco Spagnolo11, Luigi Lorini1, Cristina Gurizzan1, Paolo Bossi1|2 | 1Medical Oncology and Haematology Unit, IRCCS Humanitas Research Hospital, Rozzano MI; 2Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan; 3Medical Oncology Unit, ASST Spedali Civili, Brescia; 4Division of Medical Oncology for Melanoma, Sarcoma, and Rare Tumors, IEO, European Institute of Oncology IRCCS, Milan; 5Unit of Dermatology, Luigi Vanvitelli University of Campania, Naples; 6Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa; 7Institute of Dermatology, Catholic University of the Sacred Heart, Rome, Italy; Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome; 8Department of Health Sciences, University of Eastern Piedmont, Novara; 9Department of Dermatology and Venereology, University of Trieste, Ospedale Maggiore, Trieste; 10Department of Melanoma, Cancer Immunotherapy and Development Therapeutics, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples; 11Department of Medical Oncology, IRCCS AOU San Martino-Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy.
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26 | Tumor size may predict early response to sonidegib in locally-advanced basal cell carcinoma: clinical and histopathological correlates from a monocentric case series Gabriella Perillo1, Giovanni Cecchi1, Biancamaria Zuccaro1, Federica Fazzari1, Vincenzo De Giorgi1|2 | 1Section of Dermatology, Department of Health Sciences, University of Florence; 2Cancer Research "Attilia Pofferi" Foundation, Pistoia, Italy.
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30 | Sonidegib for nevoid basal cell carcinoma (Gorlin) syndrome and EADO stage IIb sporadic basal cell carcinomas: a phase II study (SIBLINGS trial) Sara Farinatti1|2, Giuseppe Agenziano3, Emi Dika4|5, Emanuela Passoni6, Ketty Peris7, Pietro Quaglino8, Paola Queirolo9, Massimiliano Scalvenzi10, Iris Zalaudek11, Luigi Lorini11, Cristina Gurizzan1, Monica Variolo1|2, Paolo Bossi*1|2, Carlo Resteghini*1|2 | 1Medical Oncology and Hematology Unit, IRCCS Humanitas Research Hospital, Rozzano, Milano; 2Department of Biomedical Sciences, Humanitas University, Rozzano MI; 3Unit of Dermatology, Luigi Vanvitelli University of Campania, Naples; 4Oncologic Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna; 5Department of Medical and Surgical Sciences, DIMEC, University of Bologna, Bologna; 6Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan; 7Institute of Dermatology, Catholic University of the Sacred Heart, Rome; Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome; 8Dermatologic Clinic, University of Turin Medical School, Turin; 9Medical Oncology Unit; 10Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples; 11Department of Dermatology and Venereology, University of Trieste, Ospedale Maggiore, Trieste, Italy. *Contributed equally.
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33 | A single center, real world experience with hedgehog pathway inhibitors in advanced basal cell carcinoma Giulia Gibilisco1, Ramiz Anwar Rana1, Vincenzo D’Alonzo1, Maura Colucci1|2, Monica Valente2, Elisa Cinotti3, Giovanni Rubino4, Valentina Croce1, Eleonora Carbonari1, Matteo Ravara1, Tommaso Sani1, Maria Lo Fiego1, Alessia Covre1, Serena Cutarella1, Roberto Cuomo5, Luca Grimaldi5, Pietro Rubegni3, Michele Maio1|2, Anna Maria Di Giacomo1|2 | 1University of Siena; 2Center for Immuno-Oncology, Medical Oncology and Immunotherapy, Department of Oncology, University Hospital of Siena; 3Dermatology Unit, Department of Medicine, Surgery and Neuroscience, University Hospital of Siena; 4Radiotherapy Unit, Department of Oncology, University Hospital of Siena; 5Plastic Surgery Unit, Department of Medicine, Surgery and Neuroscience, University Hospital of Siena; 6NIBIT Foundation Onlus, Genoa, Italy.
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