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31 | Effectiveness and safety of adjuvant combo-targeted and immunotherapy in melanoma patients Valentina Salizzato1, Luisa Piccin1, Alessio Fabozzi2, Paolo Del Fiore3, Francesco Cavallin4, Chiara Cacco1|5, Simone Mocellin3|5, Marcodomenico Mazza3, Valentina Guarneri1|5, Jacopo Pigozzo1 | 1Medical Oncology 2, Veneto Institute of Oncology IOV-IRCCS, Padova; 2Medical Oncology 3, Veneto Institute of Oncology IOV-IRCCS, Padova; 3Soft-Tissue, Peritoneum and Melanoma Surgical Oncology, Veneto Institute of Oncology IOV-IRCCS, Padova; 4Independent Statistician, Solagna; 5Department of Surgical, Oncological and Gastroenterological Sciences, University of Padova, Padova, Italy.
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02 | Melanoma training in primary care: comparing traditional teaching with telemedicine-enhanced education. A review Giorgia Ravaglia1, Edoardo Mora2, Debora Cantagalli3, Serena Magi4, Laura Mazzoni4, Matelda Medri4, Cesare Massone5, Davide Melandri6, Federica Zamagni7, Ines Zanna8, Gianluca Pistore9, Saverio Caini8, Salvatore Amato10, Vincenzo De Giorgi11, Pietro Quaglino12, Maria Antonietta Pizzichetta13|14, Giovanni Luigi Tripepi15, Sofia Spagnolini1, Ignazio Stanganelli1|4 | 1Dermatology Resident Training Program, Department of Medicine and Surgery, University of Parma, Parma; 2Dermatology Unit, Ospedale S. Anna, Como; 3Primary Care Resident Training program, Ausl Bologna, Bologna; 4Skin Cancer Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" – IRST Meldola, Forlì-Cesena; 5Dermatology Unit, Ospedali Galliera, Genova; 6Dermatology Unit, AUSL Romagna and University of Bologna, Cesena. 7Registro Tumori della Regione Emilia Romagna, IRCCS Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST Meldola, Forlì-Cesena; 8Clinical Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network, ISPRO, Florence; 9Clinical Epidemiology Unit, Istituto Dermopatico dell’Immacolata - IRCCS, Rome; 10Associazione Dermatologi Ospedalieri Italiani, ADOI, Sicilia and Teledermatology working group, Palermo; 11Dermatology, Department of Health Sciences, University of Florence, Florence; 12Dermatologic Clinic, Department of Medical Sciences, University of Turin, Torino; 13Department of Dermatology, University of Trieste, Trieste; 14Department of Medical Oncology, Centro di Riferimento Oncologico di Aviano, CRO, IRCCS, Aviano; 15CNR-IFC, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Reggio Calabria, Italy.
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03 | Pancreatic cancer burden in Italian CDKN2a-positive families followed for up to 25 years Eleonora Allavena1|2, Bruna Dalmasso2, Andrea Gambino2, Francesca Barbero2, Irene Vanni2, Cansu Gorgun1, Francesco Spagnolo2|4, Enrica Tanda3, Andrea Boutros3, William Bruno1|2, Lorenza Pastorino1|2, Paola Ghiorzo1|2 | 1Department of Internal Medicine and Medical Specialties - DiMI, University of Genoa; 2Cancer Genetics Unit, IRCCS Ospedale Policlinico San Martino, Genoa; 3Medical Oncology Unit, IRCCS Ospedale Policlinico San Martino, Genoa; 4Department of Surgical and Diagnostic Integrated Sciences, University of Genoa, Genoa, Italy.
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35 | Real-world outcomes of targeted therapy in stage IV melanoma after relapse on adjuvant dabrafenib and trametinib: insights from a single-center cohort Rossella Villani, Chiara Bungaro, Anna Cecere, Ileana De Roma, Sabino Strippoli, Michele Guida | Rare Tumors and Melanoma Unit, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
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22 | Surgical radicality and reconstructive techniques in melanoma and non-melanoma skin cancer A. Lenta, A. Amore, L. Benedetto, C. Caracò | Chirurgia del Melanoma e dei tumori cutanei, Istituto Nazionale Tumori "Fondazione Pascale", Napoli, Italy.
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27 | Real-world data for malignant melanoma stage II adjuvant therapy Silvana Cozzolino1, Antonino Colloca1, Miriam Forte1, Francesco Caraglia1, Alfonso Esposito1, Maria Cristina Giugliano1, Eleonora Cioli1, Marcella Scala2, Maria Chiara Sergi3, Teresa Del Giudice4, Francesca Sparano5, Immacolata Paciolla6, Mariangela Pasqualoni7, Luigi Formisano2, Stefania Napolitano1, Antonio Maria Grimaldi1, Paolo Antonio Ascierto5, Fortunato Ciardiello1, Teresa Troiani1, Vincenzo De Falco1 | 1Medical Oncology, Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples; 2Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy; 3Division of Medical Oncology, "Mons. A.R. Dimiccoli" Hospital, Barletta; 4Nuclear Medicine Unit, "Mater Domini" University Hospital, Catanzaro; 5Melanoma, Cancer Immunotherapy and Development Therapeutics Unit, Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Naples; 6Medical Oncology Unit, AORN "San Pio", Benevento, Italy; 7Medical Oncology Unit, ASL Taranto, Italy.
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12 | Integrated molecular and immunophenotypic profiling of uveal melanoma: prognostic insights and biological perspectives Francesco Fortarezza1, Giovanni Zarrilli2, Giada Munari1, Valentina Angerilli3, Mariangela Balistreri1, Luisa Piccin4, Valentina Salizzato4, Jacopo Pigozzo4, Giulia Midena5, Raffaele Parrozzani6, Valentina Guarneri4|7, Edoardo Midena5|6, Marta Sbaraglia1|8, Matteo Fassan8|9, Angelo Paolo Dei Tos1|8 | 1Surgical Pathology and Cytopathology Unit, Department of Integrated Diagnostics. Azienda Ospedale-Università Padova, Padua; 2Surgical Pathology Unit, Azienda Ulss 3 Serenissima, Ospedale dell'Angelo, Venezia; 3Department of Surgical Pathology, Azienda ULSS2 Marca Trevigiana, Treviso; 4Medical Oncology 2, Veneto Institute of Oncology, IOV-IRCCS, Padua; 5IRCCS-Fondazione Bietti, Rome; 6Department of Ophthalmology, University of Padova, Padova; 7Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua; 8Department of Medicine, University of Padua School of Medicine, Padua; 9Veneto Institute of Oncology, IOV-IRCCS, Padua, Italy.
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11 | Challenges in developing a digital pathology consultation network: insights from the MELCAYA experience Filippo Ugolini1, Dario Di Gangi2, Roberta Gugliotta3, Anna Szumera-Ciećkiewicz4|5, Llucia Alos6, Natalia Castrejón6, Stephan Forchhammer7, Barbara Valeri8, Nicolas Macagno9, Sule Ozturk Sari10, Ozge Hurdogan10, Sokol Sina11, Sylvie Fraitag12, Valerio Gaetano Vellone13, Chiara Trambaiolo13, Rita Alaggio14, Sabrina Rossi14, Giovanni Arcuri3, Daniela Massi2, Claudio Conti3 | 1Histopathology and Molecular Diagnostics, Careggi University Hospital, Florence, Italy. 2Section of Pathological Anatomy, Department of Health Sciences, University of Florence, Florence, Italy. 3UOC Direzione Tecnica, ICT ed Innovazione Tecnologie Sanitarie, Fondazione Policlinico Agostino Gemelli IRCCS, Roma, Italy. 4Biobank, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland. 5Department of Pathology , Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland. 6Department of Pathology, Hospital Clínic of Barcelona, University of Barcelona, Barcelona, Spain.7Department of Dermatology, University Medical Center, Eberhard Karls University Tübingen, Tübingen, Germany. 8Pathology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. 9Aix-Marseille University, Marmara Institute, INSERM, U1251, MMG, DOD-CET, Marseille, France. 10Department of Pathology, Istanbul University Istanbul Medical Faculty, Istanbul, Türkiye; 11Section of Pathology, Department of Diagnostics and Public Health, University of Verona, Verona, Italy. 12Pathology Department, Necker-Enfants Malades Hospital, AP-HP, Paris, France; 13Pathology Unit, IRCCS Istituto Giannina Gaslini, Genoa; 14Pathology Unit, Department of Laboratories, Bambino Gesu Children's Hospital, IRCCS, Rome, Italy.
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17 | The role of sentinel lymph node biopsy in pt1a, pt1b and pt2a melanomas: a 10-year experience through 2025 Gabriele Roccuzzo1, Nicolas Destefanis2, Giulia Orlando3, Eleonora Bergamo1, Virginia Caliendo4, Adriana Lesca5, Daniela Zugna2, Franco Picciotto4, Rebecca Senetta3, Simone Ribero1, Pietro Quaglino1 | 1Department of Medical Sciences, Section of Dermatology, University of Turin; 2Cancer Epidemiology Unit, Department of Medical Sciences, University of Turin; 3Department of Oncology, Section of Surgical Pathology, University of Turin; 4Dermatologic Surgery Section, Department of Surgery, Azienda Ospedaliera Universitaria Città della Salute e della Scienza, Turin; 5Division of Nuclear Medicine, Department of Medical Science, University of Turin, Italy.
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32 | Tebentafusp in metastatic uveal melanoma: 3 years of real world data and insights from liquid biopsy Luisa Piccin1, Maria Chiara Scaini2, Valentina Salizzato1, Cristina Catoni2, Elisabetta Di Liso1, Alice Menichetti1, Chiara Cacco1|4, Chiara Gottardi1|4, Francesca Di Sarra3, Marina Coppola3, Valentina Guarneri1|4, Jacopo Pigozzo1 | 1Medical Oncology 2 - Veneto Institute of Oncology IOV-IRCCS; 2Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV-IRCCS; 3Pharmacy Unit - Veneto Institute of Oncology IOV-IRCCS; 4Department of Surgery, Oncology and Gastroenterology, University of Padova, Italy.
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19 | Late draining lymph nodes on preoperative lymphoscintigraphy in melanoma patients: preliminary data from a retrospective study of over 400 cases Tiziano Pallara, Giovanni Marruzzo, Emilia Migliano | UOSD Chirugia Plastica ad Indirizzo Dermatologico e Rigenerativo, IRCCS IFO Istituto San Gallicano, Roma, Italy.
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25 | A phase II, open-label study to improve compliance and time of treatment after obtaining complete response through a tailored schedule of sonidegib in locally advanced basal cell carcinomas – the SONIBEC trial Monica Variolo1|2, Carlo Resteghini1|2, Sara Farinatti1|2, Andrea Alberti3, Valeria Tovazzi3, Paola Queirolo4, Maristella Saponara4, Giuseppe Argenziano5, Riccardo Marconcini6, Ketty Peris7, Paola Savoia8, Maria Chiara Tronconi1, Iris Zalaudek9, Paolo Ascierto10, Francesco Spagnolo11, Luigi Lorini1, Cristina Gurizzan1, Paolo Bossi1|2 | 1Medical Oncology and Haematology Unit, IRCCS Humanitas Research Hospital, Rozzano MI; 2Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan; 3Medical Oncology Unit, ASST Spedali Civili, Brescia; 4Division of Medical Oncology for Melanoma, Sarcoma, and Rare Tumors, IEO, European Institute of Oncology IRCCS, Milan; 5Unit of Dermatology, Luigi Vanvitelli University of Campania, Naples; 6Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa; 7Institute of Dermatology, Catholic University of the Sacred Heart, Rome, Italy; Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome; 8Department of Health Sciences, University of Eastern Piedmont, Novara; 9Department of Dermatology and Venereology, University of Trieste, Ospedale Maggiore, Trieste; 10Department of Melanoma, Cancer Immunotherapy and Development Therapeutics, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples; 11Department of Medical Oncology, IRCCS AOU San Martino-Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy.
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14 | Unraveling the transcriptomic landscape of poorly differentiated cutaneous squamous cell carcinoma: toward prognostic biomarkers Lorenzo Bellando1, Chiara Anselmo2, Giulia Orlando3, Leonardo Panarelli2, Ilaria Palma2, Virginia Caliendo3, Franco Picciotto4, Gabriele Roccuzzo5, Pietro Quaglino5, Simone Ribero5, Rebecca Senetta3 | 1Pathology Unit, Città Della Salute e Della Scienza University of Turin; 2Department of Medical Sciences, Pathology Unit, University of Turin; 3Department of Oncology, Pathology Unit, University of Turin; 4Department of Surgery, Dermatologic Surgery Section, Azienda Ospedaliera Universitaria Città della Salute e della Scienza of Turin; 5Department of Medical Sciences, Section of Dermatology, University of Turin, Italy.
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24 | Management of advanced basal cell carcinoma with hedgehog inhibitors: a real-world prospective comparative study Federico Venturi1|2|3, Biancamaria Zuccaro1, Gabriella Perillo1, Giovanni Cecchi1, Aurora Gaeta4|5, Sara Gandini4, Vincenzo De Giorgi1|6 | 1Section of Dermatology, Department of Health Sciences, University of Florence; 2Oncologic Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna; 3Department of Medical and Surgical Sciences, DIMEC, Alma Mater Studiorum University of Bologna; 4Department of Experimental Oncology, European Institute of Oncology, IRCCS, Milan; 5Department of Statistics and Quantitative Methods, University of Milano-Bicocca; 6Cancer Research "Attilia Pofferi" Foundation, Pistoia, Italy.
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30 | Sonidegib for nevoid basal cell carcinoma (Gorlin) syndrome and EADO stage IIb sporadic basal cell carcinomas: a phase II study (SIBLINGS trial) Sara Farinatti1|2, Giuseppe Agenziano3, Emi Dika4|5, Emanuela Passoni6, Ketty Peris7, Pietro Quaglino8, Paola Queirolo9, Massimiliano Scalvenzi10, Iris Zalaudek11, Luigi Lorini11, Cristina Gurizzan1, Monica Variolo1|2, Paolo Bossi*1|2, Carlo Resteghini*1|2 | 1Medical Oncology and Hematology Unit, IRCCS Humanitas Research Hospital, Rozzano, Milano; 2Department of Biomedical Sciences, Humanitas University, Rozzano MI; 3Unit of Dermatology, Luigi Vanvitelli University of Campania, Naples; 4Oncologic Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna; 5Department of Medical and Surgical Sciences, DIMEC, University of Bologna, Bologna; 6Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan; 7Institute of Dermatology, Catholic University of the Sacred Heart, Rome; Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome; 8Dermatologic Clinic, University of Turin Medical School, Turin; 9Medical Oncology Unit; 10Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples; 11Department of Dermatology and Venereology, University of Trieste, Ospedale Maggiore, Trieste, Italy. *Contributed equally.
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10 | Prognostic value of trans epidermal water loss in the treatment of actinic keratoses. A comparison amongst topical therapies for field cancerization Matteo Bevilacqua, Filippo Fanetti, Nicolò Mori, Agata Janowska, Valentina Dini, Marco Romanelli | Department of Dermatology, University of Pisa, Pisa, Italy.
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15 | Clinico-pathological features of superficial angiosarcomas: a retrospective study Lorenzo Bellando1, Chiara Anselmo2, Giulia Orlando3, Leonardo Panarelli2, Pietro Cosentino2, Pietro Quaglino4, Franco Picciotto5, Simone Ribero4, Rebecca Senetta3 | 1Pathology Unit, Città Della Salute e Della Scienza of Turin, University of Turin; 2Department of Medical Sciences, Pathology Unit, University of Turin; 3Department of Oncology, Pathology Unit, University of Turin; 4Department of Medical Sciences, Section of Dermatology, University of Turin; 5Department of Surgery, Dermatologic Surgery Section, Azienda Ospedaliera Universitaria Città della Salute e della Scienza, Turin, Italy.
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33 | A single center, real world experience with hedgehog pathway inhibitors in advanced basal cell carcinoma Giulia Gibilisco1, Ramiz Anwar Rana1, Vincenzo D’Alonzo1, Maura Colucci1|2, Monica Valente2, Elisa Cinotti3, Giovanni Rubino4, Valentina Croce1, Eleonora Carbonari1, Matteo Ravara1, Tommaso Sani1, Maria Lo Fiego1, Alessia Covre1, Serena Cutarella1, Roberto Cuomo5, Luca Grimaldi5, Pietro Rubegni3, Michele Maio1|2, Anna Maria Di Giacomo1|2 | 1University of Siena; 2Center for Immuno-Oncology, Medical Oncology and Immunotherapy, Department of Oncology, University Hospital of Siena; 3Dermatology Unit, Department of Medicine, Surgery and Neuroscience, University Hospital of Siena; 4Radiotherapy Unit, Department of Oncology, University Hospital of Siena; 5Plastic Surgery Unit, Department of Medicine, Surgery and Neuroscience, University Hospital of Siena; 6NIBIT Foundation Onlus, Genoa, Italy.
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26 | Tumor size may predict early response to sonidegib in locally-advanced basal cell carcinoma: clinical and histopathological correlates from a monocentric case series Gabriella Perillo1, Giovanni Cecchi1, Biancamaria Zuccaro1, Federica Fazzari1, Vincenzo De Giorgi1|2 | 1Section of Dermatology, Department of Health Sciences, University of Florence; 2Cancer Research "Attilia Pofferi" Foundation, Pistoia, Italy.
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